UNIVERSITY OF BUCHAREST
FACULTY OF PHYSICS

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2024-11-22 1:32

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Conference: Bucharest University Faculty of Physics 2010 Meeting


Section: Nuclear and Elementary Particles Physics


Title:
Cross section calculations of 124I population in proton and deuteron induced reactions


Authors:
Elena Giubega, Mihaela Sin


Affiliation:
Faculty of Physics, University of Bucharest


E-mail
giubega_elena@yahoo.com


Keywords:
Iodine-124,Charged particle induced reaction, Cross section,Excitation function, Nuclear model calculation.


Abstract:
The nuclear model code EMPIRE has been used to estimate the production cross sections of several therapeutic radioisotopes via different routes in the attempt to improve the accuracy and completeness of the data needed for their optimum production. One of the most important emerging therapeutic radionuclides that allows a combination of therapy and positron emission tomography is 124I. In this paper the following production routes of this radionuclide have been studied: 124Te(p,n) 124I, 124Te(d,2n) 124I, 125Te(p,2n) 124I. The following models implemented in EMPIRE code have been used to describe the reaction mechanisms: (i) the spherical optical model for the calculation of direct cross sections and the particle transmission coefficients for the incident and outgoing channels, (ii) Hauser-Feshbach statistical model considering multiple-particle emission and full gamma-cascade for the treatment of the compound nucleus mechanism and (iii) the one-component exciton model to calculate nucleon, gamma and cluster pre-equilibrium emission. The input parameters were retrieved from internal systematics or from the Reference Input Parameter Library – RIPL3 and adjusted to fit the experimental data.For all three cases, complete sets of cross sections for all reaction channels in the energy range 1-30 MeV are provided. The results are very all supported by all available experimental data. They are formatted in the standard form (ENDF-6) to permit retrieval, graphical and checking capabilities. Providing accurate and complete nuclear data is essential for the production of medical radioisotopes with the specific activity and purity required for efficient and safe clinical purposes.