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UNIVERSITY OF BUCHAREST
FACULTY OF PHYSICS Guest
2024-11-24 11:49 |
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Conference: Bucharest University Faculty of Physics 2005 Meeting
Section: Atomic and Molecular Physics; Astrophysics
Title:
Modeling sepsis by non linear dynamic evolution equations
Authors:
Mircea V. Rusu (1), Elena Stancu (2), Alexandru Curutiu (3)
Affiliation:
(1), (3), Faculty of Physics, University of Bucharest
E-mail
mrusu@dnt.ro, alexcurutiu@yahoo.com
Keywords:
sepsis, Brouse model
Abstract:
In bioinformatics, biochemical pathways can be modeled by many differential equations. It is still an open problem how to fit the huge amount of parameters of the equations to the available data. Here, the approach of systematically learning the parameters is necessary. In this communication, we describe an example of modeling an inflammatory case important in so-called sepsis. Due to the nonlinear dynamics evolution in sepsis a general approaches is necessary to fit the parameters for sparse, given data. We present the computer code of the Brouse model.
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