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UNIVERSITY OF BUCHAREST
FACULTY OF PHYSICS Guest
2024-11-23 18:10 |
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Conference: Bucharest University Faculty of Physics 2014 Meeting
Section: Biophysics; Medical Physics
Title:
Dose distribution of therapeutic proton beam in presence of metallic implant: model predictions and experimental data
Authors:
Cristina OANCEA(1,2), K. SHIPULIN(2), G. MYTSIN(2), A. BARBORICA(1), Luchin IVANOVICH (2), A. MOLOKANOV(2), Dorota Maria BOROWICZ(2)
Affiliation:
1) Department of Biophysics, Electricity and Solid State, Faculty of Physics, University of Bucharest, Atomistilor Street 405, 077125 Bucharest-Magurele, Ilfov Region, Romania
2) Laboratory of Nuclear Problems, Joint Institute for Nuclear Research, 6 Joliot-Curie Street, 141980, Dubna, Moscow Region, Russia
E-mail
oancea@jinr.ru
Keywords:
Proton therapy, dose distribution, metallic implant, Monte Carlo, FLUKA, EBT2
Abstract:
The purpose of this work was to evaluate the effect of dose perturbation caused by metallic implants and to find a way to reduce the errors of dose calculation. We performed the dosimetric experiments in case of proton beam therapy in order to measure the dose distribution. In a water phantom were inserted Gafchromic EBT2 films and the metallic implant situated in the center of films in a vertical position. The implant consists of titanium alloy with density = 3.9 g/cm3 and diameter of 5 mm. The initial energy 173 MeV was decreased using 52.5 mm and 165 mm water equivalent of plexiglass.Monte Carlo simulations based on the FLUKA code and calculations in two different 3D treatment planning systems (one from Loma Linda Cancer Center, California, USA and the other conceived at the Medico-Technical Complex, JINR, Dubna, Russia) have been carried out, under the same conditions, in order to address the feasibility. Comparison of numerical results with experimental data led to recognition of small differences in dose distribution caused by CT scan. In case of calculation of dose distribution for targets which contained metallic implants it is recommended to exclude this area from the direction of radiation field.
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