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UNIVERSITY OF BUCHAREST
FACULTY OF PHYSICS Guest
2024-11-27 9:35 |
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Conference: Bucharest University Faculty of Physics 2014 Meeting
Section: Optics, Spectroscopy, Plasma and Lasers
Title:
Matrix Assisted Pulsed Laser Evaporation and Dip Coating deposition of polymers thin films for biomedical applications
Authors:
C.NITA(1), A.VISAN(1), C.BREAZU(3), G.SOCOL(1)
Affiliation:
1) National Institute for Lasers, Plasma and Radiation Physics, Magurele, Ilfov, Romania
2) Faculty of Physics, University of Bucharest, Magurele, Ilfov, Romania
3) National Institute of Materials Physics, Magurele, Ilfov, Romania
E-mail
cristina.nita@inflpr.ro
Keywords:
thin films, polymers, biomedical applications
Abstract:
We report successful transfer by MAPLE and Dip Coating of PCL and PLA, and mixtures of the two compounds (25-75%, 50-50%, and 75-25%), in order to identify an optimum compositional blending with respect to theirs structural, morphological, and wettability properties. During the last decades, polycaprolactone (PCL) and Poly(L-lactide) (PLA) have been extensively studied for controlled delivery of small molecule drugs, proteins and other macromolecules mainly due to theirs biocompatibility. Moreover, it was revealed that these materials ranked in terms of their rate of degradation, due to theirs different crystalline structure and hydrophobic to hydrophilic characteristics.Fourier transform infrared (FTIR) spectroscopic results confirmed for both deposition methods the preservation of the chemical composition while the X-ray diffractograms revealed the diffraction peaks typical for PCL and PLA polymers. SEM images showed a surface morphology of coatings which strongly depends on the polymeric mixture ratio and deposition parameters. Wettability tests performed on PCL/PLA coatings exhibited a hydrophilic behaviour.These results demonstrate the potential of using the composite films for biomedical applications.
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