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UNIVERSITY OF BUCHAREST
FACULTY OF PHYSICS Guest
2024-11-22 2:37 |
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Conference: Bucharest University Faculty of Physics 2015 Meeting
Section: Biophysics; Medical Physics
Title:
Influence of pinnacle volumetric modulated arc therapy specific parameters on nasopharynx cancer plan quality
Authors:
Mihai SUDITU (1,2), Raducu POPA (1,2), Daniela ADAM (2), Violeta CIOCALTEI (2)
Affiliation:
1) Faculty of Physics
2) Amethyst Radiology Therapeutic Center
E-mail
suditu.mihai@yahoo.com
Keywords:
volumetric modulated arc therapy, radiation therapy, cancer
Abstract:
Abstract:
Volumetric modulated arc therapy (VMAT) is a rotational intensity modulated radiation therapy technique. VMAT uses high energy linear accelerator with dynamic multileaf collimators, variable dose rate and variable gantry speed for radiation dose delivery. Pinnacle „SmartArc” optimization algorithm was developed as a solution for VMAT inverse planning, but is still unclear how varying specific SmartArc parameters can affect the plan quality.
The purpose of this study was to evaluate the influence of commissioning and planning parameters in plan quality. Commissioning parameters contain gantry speed, leaf speed and dose rate, and available planning parameters using SmartArc algorithm include number of arcs, arc length, total delivery time, collimator angle, and final gantry spacing.
For evaluation of influence of each parameter on the plan quality , ten patients with nasopharynx cancer were selected, and for each patient was created a set of plans. A reference plan was created by using a set of parameters that provided clinically acceptable plans. Each planning parameter was independently varied while keeping all other parameters set to reference values.
Modification of several parameters had small effect on plan results, but certain parameters, like arc length and total delivery time, create significant change in plan quality.
References:
Bortfeld T and Webb S 2009 Single-Arc IMRT? Phys Med Biol 54 N9-20;
Friberger H 2009 SmartArc in Pinnacle 9: A description of the algorithm RaySearch Laboratories
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