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UNIVERSITY OF BUCHAREST
FACULTY OF PHYSICS Guest
2024-11-23 17:58 |
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Conference: Bucharest University Faculty of Physics 2017 Meeting
Section: Physics and Technology of Renewable and Alternative Energy Sources
Title:
Colorimetric sensors based on organic dyes for medical applications
Authors:
Ionita DUCU (1), Valentina-Mihaela DUCU (1), Stefan-Marian IORDACHE(2), Ana-Maria IORDACHE (2)
Affiliation:
1)University of Bucharest, Faculty of Physics, SERA master, Atomistilor 405, Magurele, 077125, Ilfov, Romania
2) University of Bucharest, Faculty of Physics, 3Nano-SAE Research Center, Atomistilor 405, Magurele, 077125, Ilfov, Romania
E-mail
stefan@3nanosae.org
Keywords:
colorimetric sensor, C. albicanis, E. coli, organic dyes
Abstract:
Acute medical diseases demand rapid intervention and treatment, every delay inducing a higher morbidity and an additional risk for the patient. In the field of obstetrics and pediatric medicine, pathogenic species are especially dangerous since they produce infections in pregnant mothers (infections that are usually transmitted to the fetus) or in infants (their body is often small and unable to produce a large quantity of antibodies to fight-off the infection). The golden standard for identification of the infection vector is blood culture, a process which takes up to a few days.
Since the infected patient is prone to complications and sepsis, induced by untreated infections, the emergency field needs rapid and accurate sensors for identification of pathogen species. The colorimetric sensors provide a simple, cheap and disposable alternative to conventional detection methods. In this study, we focus on the development of a colorimetric sensor array, based on several organic dyes, for the detection of Candida albicanis (the most common fungal infection in pregnant women) and E-coli (common gastro-intestinal infection in children).
Acknowledgement:
S.-M. Iordache was supported by grant PCCA 142/2014 of the Romanian National Authority for Scientific Research.
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