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UNIVERSITY OF BUCHAREST
FACULTY OF PHYSICS Guest
2024-11-24 22:12 |
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Conference: Bucharest University Faculty of Physics 2018 Meeting
Section: Polymer Physics
Title:
Physico-chemical characterization and antifungal activity of CeHAp layers obtained by thermal evaporation
Authors:
Simona Liliana ICONARU (1), Rodica GHITA (1), Carmen Mariana CHIFIRIUC (2), Andreea GROZA (3), Alina Mihaela PRODAN (4,5), Mircea BEURAN (4,5), Monica Luminita BADEA (6), Roxana TRUSCA (7), Emil-Stefan BARNA (8), Daniela PREDOI (1)
Affiliation:
1) National Institute for Materials Physics, P.O. Box MG 07, Bucharest, Magurele, Romania
2) Microbiology Department, Faculty of Biology, University of Bucharest and Life, Environmental and Earth Sciences Division, Research Institute of the University of Bucharest (ICUB), 91-95 Splaiul Independentei, Bucharest, Romania
3) National Institute for Laser, Plasma and Radiation Physics, 409 Atomistilor Street, P.O. Box MG 36, 077125 Magurele, Romania
4) Carol Davila University of Medicine and Pharmacy, 8 Eroii Sanitari, Bucharest, Romania
5) Emergency Hospital Floreasca, Bucharest 5, Calea Floreasca Nr 8, Sector 1, Bucharest, Romania
6) University of Agronomic Sciences and Veterinary Medicine, Faculty of Horticulture, 59 Mărăşti Blvd., 011464 Bucharest, Romania
7) Faculty of Applied Chemistry and Material Science, Politehnica University of Bucharest, 1-7 Gh Polizu Street, 011061 Bucharest, Romania
8) University of Bucharest, Faculty of Physics, P.O.Box MG 11, Bucharest, Magurele, Romania
E-mail
simonaiconaru@gmail.com
Keywords:
cerium, hydroxyapatite, layer, Candida albicans
Abstract:
Cerium doped hydroxyapatite (Ce:HAp) nanopowders with xCe=0.05 were used for the preparation of Ce:HAp layers by thermal evaporation technique. The Ce:HAp (xCe=0.05) nanopowders were deposited by thermal evaporation technique on Si substrate. The cerium doped hydroxyapatite layers were characterized by Scanning Electron Microscopy (SEM) and Fourier Transform Infrared Spectroscopy (FT-IR). By infrared spectroscopy analyses, the phase composition of the cerium doped hydroxyapatite Ce:HAp layers was investigated.
The FTIR spectra of Ce:HAp layers revealed the peak characteristic to the presence of ν2 phosphate mode at 472 cm-1, the peaks resulting from the ν4 vibration of the P-O mode, ν1 symmetric P-O stretching vibration and ν3 P-O stretching vibration of PO43-. The antifungal activity of Ce:HAp layers was also investigated using Candida albicans ATCC 10231 strain.
The results of the antifungal assay evidenced that development of the fungal cells on the Ce:HAp layers has decrease for the surveyed time intervals (24,48 and 72 h) . The preliminary results obtained in this study emphasized that the Ce:HAp layers have great potential in the biomedical application field regarding biomaterials with antifungal properties.
Acknowledgement:
The studies reported in this paper have been funded by UEFISCDI through PN III 43PCCDI/2018 project.
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