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UNIVERSITY OF BUCHAREST
FACULTY OF PHYSICS Guest
2024-11-24 21:12 |
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Conference: Bucharest University Faculty of Physics 2018 Meeting
Section: Physics and Technology of Renewable and Alternative Energy Sources
Title:
Sensor-based on CNTs functionalized with porphyrin structures for neurotransmitter detection
Authors:
Valentina-Mihaela RADU(1), Stefan-Marian IORDACHE(2), Ana-Maria IORDACHE(2), Catalin BERLIC (2)
Affiliation:
1) University of Bucharest, Faculty of Physics, Magurele, Romania
2) University of Bucharest, 3Nano-SAE Research Centre, P.O. Box MG- 38, Magurele, Romania
E-mail
stefan@3nanosae.org
Keywords:
CNT, porphyrin, neurotransmitter, screen-printed electrode.
Abstract:
Neurotransmitters are biological components which facilitate the transmission of electrical signals between neurons and play an important role in the exchange of information between the brain and body. Variation in the production or metabolism of the neurotransmitters has been linked to different mental disorders such as Alzheimer’s and Parkinson’s diseases, schizophrenia, epilepsy, and paranoia. There is an increased need for the development of a fast and cheap type of sensor that can detect analytes in the biological matrix, without other purification and isolation steps. In the present study, we focus on the development and characterization of a screen-printed sensor based on CNTs functionalized with metalloporphyrins for the identification of certain neurotransmitters (dopamine, serotonin, and epinephrine). The sensors showed high sensibility and a fast response time towards neurotransmitters due to an electron-transfer reaction mechanism.
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