UNIVERSITY OF BUCHAREST
FACULTY OF PHYSICS

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2024-11-24 11:22
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Conference: Bucharest University Faculty of Physics 2021 Meeting


Section: Biophysics; Medical Physics


Title:
Monte Carlo study of doses produced by different nuclear radiations in radiotherapy


Authors:
Andreea-Cristina POPA, Oana RISTEA


Affiliation:
University of Bucharest, Faculty of Physics, P.O.Box MG-11, 077125 Bucharest-Magurele, Romania


E-mail
itsdreapopa@gmail.com


Keywords:
Monte Carlo, ion beams, simulation, hadrontherapy, SRIM, GEANT4


Abstract:
Protons and heavy ion beams at high energies, due to the specific interaction mechanisms with matter, have some advantages in the treatment of deep local cancer, as compared to the photon or electron beams that are usually used in traditional radiotherapy. A special feature of hadron therapy is low entrance dose in tissue and the Bragg peak which represents the maximum delivered dose towards the range’s end. Additionally, heavy ions have a higher biological efficiency in the Bragg peak region, generated by intense ionization and in conjunction with a lower cell repair rate make them the perfect candidate for radiotherapy of local tumours. GEANT4 (Geometry ANd Tracking) and SRIM (Stopping and Range of Ions in Matter) Monte Carlo codes were used to simulate different ion beams striking different types of tissues and to study the stopping power and the range of analyzed ions. We will present the results of the simulations of protons and heavier ions (C-12 and O-16) in different materials using the mentioned Monte Carlo codes. The interactions of these ions have been studied in bone tissue, blood, and striated muscles for a wide energy range (50-300 MeV per nucleon). The energy and material dependence of the stopping power, Bragg curve, and range of protons, C-12 and O-16 ions will be presented. Both simulation code data and the obtained results are similar. Due to the higher electric charge, the heavier ions energy loss per unit length is larger compared to the proton dE/dx, for all studied energies.