UNIVERSITY OF BUCHAREST
FACULTY OF PHYSICS

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2024-11-24 11:54

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Conference: Bucharest University Faculty of Physics 2021 Meeting


Section: Biophysics; Medical Physics


Title:
End-to-end IMRT evaluation using the CIRS thorax phantom


Authors:
Andreea Alexandra UDREA (1,2), Mihai DUMITRACHE (1), Alina DUMITRACHE (1), Maria VLĂSCEANU (1), Aurel POPESCU (2)


*
Affiliation:
1) Emergency Central Military Hospital ”Dr. Carol Davila”, Bucharest, Romania

2) University of Bucharest, Faculty of Physics, Măgurele, Romania



E-mail
andreeaaudrea@gmail.com


Keywords:
end-to-end test, intensity modulated radiation therapy, point dose, uncertainty, patient specific quality assurance


Abstract:
The purpose of this study was to evaluate the intensity modulated radiation therapy (IMRT) treatment chain using the ”end-to-end” approach, i.e. following the pathway similar to that of a real patient, through imaging, treatment planning, and dose delivery. For this work, a CIRS Thorax Phantom 002LFC which represents an average human torso in proportion, density, and 2D structure, was used. The dose-volume objectives and constraints were selected according to those currently used by eight radiotherapy (RT) centers participating in International Atomic Energy Agency (IAEA) Coordinated Research Project (CRP) E24017 Program. Point dose measurements were performed with the Semiflex 0.125 cc ionization chamber in different locations into the phantom: the planning target volume (PTV) and organs at risk (OARs) followed by a 2D dose distribution measurement with a diode array. The combined standard uncertainties (k = 1) associated with the dose measurements were calculated. Overall, the results showed that that in our radiotherapy department, an accurate treatment delivery, within the recommended tolerance, is achieved, thus confirming a high quality of IMRT clinical implementation.