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UNIVERSITY OF BUCHAREST
FACULTY OF PHYSICS Guest
2024-11-24 21:14 |
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Conference: Bucharest University Faculty of Physics 2021 Meeting
Section: Polymer Physics
Title:
Development and characterization of new ZnO materials for biomedical applications
Authors:
Mircea BEURAN (1,2), Daniela PREDOI (3), Simona Liliana ICONARU (3), Carmen Steluta CIOBANU (3), Anton FICAI (4,5,6), Bogdan Stefan VASILE (4,7), Ionela Andreea NEACSU (4,7), Ecaterina ANDRONESCU (4), Carmen Mariana CHIFIRIUC (6,8,9), Prodan Alina MIHAELA (1, 2)
Affiliation:
1) Department of Surgery, Carol Davila University of Medicine and Pharmacy, 8 Eroii Sanitari, Sector 5, 050474 Bucharest, Romania
2) Emergency Hospital Floreasca Bucharest, 8 Calea Floresca, 014461 Bucharest, Romania
3) Multifunctional Materials and Structures Laboratory, National Institute of Materials Physics, Atomistilor Street, No. 405A, P.O. Box MG 07, 077125 Magurele, Romania;
4) Department of Science and Engineering of Oxide Materials and Nanomaterials, Faculty of Applied Chemistry and Material Science, University Politehnica of Bucharest, Bucharest, Romania
5) National Centre for Micro- and Nanomaterials, University POLITEHNICA of Bucharest, 060042 Bucharest, Romania
6) Academy of Romanian Scientists, 060042 Bucharest, Romania
7) National Research Center for Micro and Nanomaterials, Faculty of Applied Chemistry and Materials Science, University Politehnica of Bucharest, 060042 Bucharest, Romania
8) Life, Environmental and Earth Sciences Division, Research Institute of the University of Bucharest (ICUB),University of Bucharest, 060023 Bucharest, Romania
9) Microbiology Department, Faculty of Biology, University of Bucharest, 1–3 Portocalelor Lane,
77206 Bucharest, Romania
*corresponding author: prodan1084@gmail.com
E-mail
prodan1084@gmail.com
Keywords:
ZnO powders, biomedical applications, antimicrobial properties
Abstract:
Bacterial infections are a serious health problem, and can lead to economic and social complications. ZnO nanostructures show significant antibacterial activity on a wide range of bacterial species explored by a large number of researchers. In this research were obtained ZnO powders (Zn2+ concentration was 0.3488 and 0.1744 (mol/L)) by a hydrothermal method in the microwave field. In the XRD diffractograms obtained on ZnO samples, the presence of well-defined diffraction maxima is observed, with high intensities, proving a high degree of crystallinity. It can be seen that in all diffractograms zinc oxide is present as a single phase, no diffraction interference being detected that corresponds to other minor phases. The results of electron microscopy studies indicate the presence of polycrystalline materials, with a high degree of crystallinity, in accordance with the structural aspects previously identified in X-ray diffractograms. From a morphological point of view, the nanoparticles obtained have a platelet and rod appearance, with thicknesses up to 50 nm, arranged mainly in the form of agglomerates, due to the large specific surface area associated with the nanometric dimension. FTIR spectra show a well-defined absorption band, characteristic of the Zn-O bond tensile vibration around 400 cm-1. The results of antimicrobial tests show visible antimicrobial effects on C. Albicans. Also, was noticed that the antimicrobial activity of ZnO powders is strongly influenced by de Zn2+concentration. The results obtained in this preliminary study are promising and create the premises for a possible use of new materials based on zinc oxide in biomedical applications.
Acknowledgement:
This work was supported by the Romanian Ministry of Research and Innovation through the project PN-III-P2-2.1-PED-2019-1375 contract no. 331PED/2020.
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