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UNIVERSITY OF BUCHAREST
FACULTY OF PHYSICS Guest
2024-11-22 2:14 |
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Conference: Bucharest University Faculty of Physics 2021 Meeting
Section: Physics and Technology of Renewable and Alternative Energy Sources
Title:
The impact of pharmaceutical compounds on the water environment
Authors:
Ioana Diana SOMOIAG(1), Cornelia NICHITA(1,2)
Affiliation:
1)University of Bucharest, Faculty of Physics, 3Nano-SAE Research Center, MG-38, 405 Atomistilor Street, 077125, Magurele, Romania
2)National Institute for Chemical – Pharmaceutical Research and Development, 112 Vitan Avenue, 031299, Bucharest, Romania
E-mail
cornelia.nichita@unibuc.ro, cornelia@3nanosae.org
Keywords:
pharmaceutical compounds, pharmaceutical pollution, water environment
Abstract:
Environment and health are directly or indirectly affected by pharmaceutical effluents especially in the adiacent of pharma industrial zones. Most large pharmaceutical companies pollute the environment, a significant problem in waste management being generated third-party companies that manufacture and supply important components of drugs (active pharmaceutical ingredients). There is ample evidence that pharmaceutical pollution has become a global problem. As a result, even drinking water sources have been contaminated with measurable amounts of hazardous chemicals which include therapeutic drugs, phytotherapeutics, biotechnological products, veterinary drugs. Different classes of pharmaceutical compounds like analgesic, antidepressant, antihypertensive, contraceptive, antibiotic, steroids and hormones have been detected in water samples between concentration ranges ng/L to μg/L. In this context, the present paper aims at an extensive study on the impact of pharmaceutical compounds on the environment. This review presents the dynamics and the development of research over the past ten years about the presence of non-steroidal anti-inflammatory analgesics, antihypertensives, antibiotics and other drugs in water. In addition, physical and chemical properties of the active pharmaceutical ingredients are highlighted such as: n-octanol-water partition coefficient(Kow), solid–water distribution coefficient(Kd) distribution and solubility.
Acknowledgement:
The support from the 3 Nano-SAE Research Centre, Faculty of Physics, University of Bucharest, are thankfully acknowledged.
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