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UNIVERSITY OF BUCHAREST
FACULTY OF PHYSICS Guest
2024-11-22 1:50 |
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Conference: Bucharest University Faculty of Physics 2021 Meeting
Section: Physics and Technology of Renewable and Alternative Energy Sources
Title:
Pharmaceutical applications and Bio-synthesis strategies to design colloidal silver solutions
Authors:
Cornelia NICHITA (1,2)
Affiliation:
1)University of Bucharest, Faculty of Physics, 3Nano-SAE Research Center, MG-38, 405 Atomistilor Street, 077125, Magurele, Romania
2)National Institute for Chemical – Pharmaceutical Research and Development, 112 Vitan Avenue, 031299, Bucharest, Romania
E-mail
cornelia.nichita@unibuc.ro; cornelia@3nanosae.org
Keywords:
colloidal silver, bioreduction mechanisms, polyphenolic compounds
Abstract:
Silver nanoparticles (AgNPs) have been exploited in a wide range of potential applications in medicine, cosmetics, renewable energies, environmental remediation, and biomedical devices. Also colloidal silver nanoparticles (AgNPs) have applications in the pharmaceutical area due to its antibacterial, antifungal and antiviral properties as well as due to the possibility of use as a transport vector for drugs or natural compounds.This contribution of present paper focuse on the biosynthesis strategy of AgNPs with polyphenolic components from plant extracts, but also on the possibility of using these nanoparticles as transport systems. The aim of the study is to investigate the relation between the bioreduction mechanisms and the composition of the polyphenolic components: total phenolic contents (TPC) quantified in equivalent gallic acid, total flavonoid contents (TFC) expressed quantified in equivalent rutin. Are analyzed the polyphenols extracts from Ocimum basilicum L., their bioreduction kinetics and the specific mechanisms. The design and obtain kinetics, as well as the specific characteristics of AgNPs: surface plasmon resonance, Mie scattering, size, zeta potential, are analyzed by UV-VIS spectroscopy and dinamic light scattering (DLS) technique.
Acknowledgement:
This paper was supported by the Romanian National Authority for Scientific Research, UEFISCDI Project 40PCCDI/2018, PN 16270303/2017
The support from the 3 Nano-SAE Research Centre and the support from the Materials and Devices are thankfully acknowledged.
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