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UNIVERSITY OF BUCHAREST
FACULTY OF PHYSICS Guest
2024-11-24 11:33 |
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Conference: Bucharest University Faculty of Physics 2021 Meeting
Section: Biophysics; Medical Physics
Title:
Scintigraphy and its role in medical imaging
Authors:
Alina Mihaela PĂUNOIU (1), Mihaela Raluca MITITELU (2), Maria Alina GHERMAN (2), Alexandru JIPA (1)
Affiliation:
1. Faculty of Physics, University of Bucharest
2. The Central Military Emergency University Hospital „Dr. Carol Davila” Bucharest
E-mail
alinapaunoiu23@yahoo.com
Keywords:
diagnosis, scintigraphy, radiopharmaceutical, distribution, SPECT/CT
Abstract:
Modern nuclear imaging methods have become indispensable tools in investigating and treating various diseases. The widespread use of SPECT (Single Photon Emission Computed Tomography) and PET (Positron Emission Tomography), fused with CT (Computerized Tomography) are key technologies, which provide ample information in terms of diagnosis. A more specific, non-invasive, imaging technique is scintigraphy, employed to locate certain anomalies in the body, related to either bones or soft tissues. The aim of this study was to highlight the importance of scintigraphy by observing the distribution of radioactivity of several radiopharmaceuticals. Each one corresponds to a different type of investigation, namely of bone, salivary gland, kidney, parathyroid and neuroendocrine system. The radiotracers employed were 99mTc – HDP, 99mTc – pertechnetate, 99mTc – DTPA, 99mTc – MIBI, 99mTc – Tektrotyd. They were delivered to the patients, taking into consideration factors such as weight, in the case of bone scintigraphy, and dose limits, specific to each acquisition protocol. Once injected, the radiopharmaceuticals accumulate in target organs and emit gamma rays, which are detected by a pair of gamma cameras belonging to a SPECT/CT scanner. The resulting scintigrams provided valuable information about the structure and function of the areas of interest. Parathyroid and neuroendocrine scintigraphies implied the additional use of hybrid SPECT/CT technology, which offered more accurate results due to its high image quality.
References:
[1] A. Giussani, C. Hoeschen (2013) Imaging in Nuclear Medicine, Edition Springer
[2] T. K. Gupta (2013) Radiation, Ionization, and Detection in Nuclear Medicine, Edition Springer
[3] D. Delbeke, O. Israel (2010) Hybrid PET/CT and SPECT/CT Imaging, Edition Springer
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