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UNIVERSITY OF BUCHAREST
FACULTY OF PHYSICS Guest
2024-11-23 18:08 |
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Conference: Bucharest University Faculty of Physics 2022 Meeting
Section: Theoretical Physics and Applied Mathematics
Title:
Optical Tweezers
Authors:
Miruna-Ioana BELCIU, Mădălina BOCA
Affiliation:
Faculty of Physics, University of Bucharest
E-mail
mirunaioanabel@gmail.com
Keywords:
optical trapping, optical tweezers, electromagnetic scattering, red blood cell, laser guiding, optical forces, Lorentz-Mie theory
Abstract:
Optical tweezers are systems based on precisely shaped and focused laser beams used to hold, move and manipulate microscopic particles, just as the “normal” tweezers would move macroscopic objects.
In 2018 the Nobel prize for Physics was awarded to Gérard Mourou and Donna Strickland "for their method of generating high-intensity, ultra-short optical pulses" and to Arthur Ashkin "for the optical tweezers and their application to biological systems".
In my talk I will present, in the first part, the general theory of optical tweezers. There are two limiting cases: Rayleigh optical trapping regime for particles much smaller than the radiation wavelength, and the geometrical optics regime for very large particles. In the intermediate case, when the particle size is of the same order of magnitude as the radiation wavelength, optical forces can be described in the framework of the generalized Lorenz Mie theory.
In the second part I will discuss an application of optical tweezers for the study of some biophysical properties of human red blood cells.
In conclusion, this field has been in great expansion due to the emergence of numerous possibilities to manipulate and characterize nanometric and micrometric objects of interest leading to remarkable theoretical and practical understanding of phenomena occurring at these scales.
References:
Philip Jones, "OPTICAL TWEEZERS", Cambridge University Press, 2015
M.S.Rocha, "Optical tweezers for undergraduates: Theoretical analysis and experiments", American Journal of Physics, August 2009, DOI: 10.1119/1.3138698
"Optical Tweezers in Studies of Red Blood Cells"
Ruixue Zhu 1, Tatiana Avsievich, and Alexey Popov and Igor Meglinski, Cells 2020, 9, 545; doi:10.3390/cells9030545
arXiv:1402.5439v1 [physics.optics] 21 Feb 2014
"Micromanipulation by Light in Biology and Medicine The Laser Microbeam and Optical Tweezers"- Karl Otto Greulich, 1999
Acknowledgement:
I am especially greatful for the guidance and support of Conf. univ. dr. Madalina Boca.
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