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UNIVERSITY OF BUCHAREST
FACULTY OF PHYSICS Guest
2024-11-23 17:44 |
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Conference: Bucharest University Faculty of Physics 2022 Meeting
Section: Biophysics; Medical Physics
Title:
The benefits of CT Simulation with Deep Inspiration Breath Hold tehnique for breast cancer radiotherapy
Authors:
Gratiela NITESCU (1,2), Madalina CROITORIU(2), Andrei BARBORICA(1)
Affiliation:
1) Faculty of Physics, University of Bucharest, Măgurele, Romania
2) MNT Healthcare Europe SRL
E-mail
gratiela.nitescu@gmail.com
Keywords:
CT simulation, DIBH, IMRT, radiotherapy, breast cancer
Abstract:
Radiation revolutionized medicine when it was first used to treat cancer in 1901. Its use, however, has only been able to evolve as far as technical innovation has allowed. Now, thanks to progress in physics, technology and computing, radiation therapy is entering a new era of precision, effectiveness and safety. The goal of radiotherapy is to safely maximize the treatment of a tumour using radiation, while minimizing harm to the patient’s nearby normal tissue and critical organs. This work describes a CT simulation technique that significantly reduces cardiac toxicity associated with decreased average dose in the heart but also in the lungs: Deep Inspiration Breath Hold (DIBH). The Intensity Modulated Radiation Therapy (IMRT) treatment technique is also captured and described. DIBH is useful in situations where radiotherapy is needed in the thoracic region and comes with advantages over free breathing treatment: better accuracy of treatment delivered (as respiratory movement is removed), reduction of lung toxicity and especially reduction of heart toxicity, thus decreasing risk of cardiac mortality and acute coronary events. The work is based on a comparison between the two treatment methods (Free Breathing and Deep Inspiration Breath Hold) following the analysis of treatment plans for a sample of breast cancer patients. The obstacle of the method is that not all patients will be able to hold their breath for (30-40) s, the time required for the CT simulation but also for the delivery of the treatment at each radiotherapy session. Patients are encouraged and guided to practice deep-inspiring exercises, and the benefits of this simulation and treatment technique have been seen in dosimetric analysis.
References:
1. Faiz M. Khan, John P. Gibbons (2014) The Physics of Radiation Therapy
2. Walter and Miller’s Textbook of Radiotherapy - Radiation Physics, Therapy and Oncology (seventh edition - 2012)
3. Bergom, C., Currey, A., Desai, N., Tai, A., & Strauss, J. B. (2018). Deep Inspiration Breath Hold: Techniques and Advantages for Cardiac Sparing During Breast Cancer Irradiation. Frontiers in oncology, 8, 87.
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