UNIVERSITY OF BUCHAREST
FACULTY OF PHYSICS

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2024-11-23 18:30

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Conference: Bucharest University Faculty of Physics 2023 Meeting


Section: Biophysics; Medical Physics


Title:
Antioxidant activity of ZnO nanoparticles doped with Gd3+


Authors:
Andra-Cătălina STĂNESCU(1,2), Mariana ȘTEFAN(1),Vasile BERCU(2)


Affiliation:
1)National Institute of Materials Physics, Atomistilor Street 405A, POB MG 7, 077125 Bucharest, Romania

2)Department of Electricity, Solid Physics and Biophysics, Faculty of Physics, University of Bucharest, Măgurele, Romania


E-mail
stanescuandra99@yahoo.com


Keywords:
Resonance spectroscopy, nanoparticles, free radicals, antioxidant


Abstract:
Zinc oxide nanoparticles (ZnO) are among the most investigated metal oxide nanoparticles and have emerged as a promising material in the fields of optical, electrical, food packaging, and biomedical applications due to their biocompatibility, low toxicity, and low cost. These nanoparticles possess strong biological activity and are in use for various biological applications in several industries (as antimicrobial, antioxidant, antidiabetic, anticancer, anti-inflammatory, photocatalytic, wound healing and drug delivery agent). This study evaluates the free radical scavenging properties of the ZnO nanoparticles doped with different concentrations of Gd3+. For the analysis of the antioxidant activity we have used the Electron Paramagnetic Resonance (EPR) spectroscopy to perform a 2,2–diphenyl-1-picrylhydrazyl hydrate (DPPH) assay, on four samples of ZnO nanoparticles, pure and doped with Gd3+. The ZnO scavenging activity was determined to be stronger at lower Gd3+ concentrations.