| |
 |
UNIVERSITY OF BUCHAREST
FACULTY OF PHYSICS Guest
2024-11-23 17:41 |
 |
|
|
|
Conference: Bucharest University Faculty of Physics 2023 Meeting
Section: Biophysics; Medical Physics
Title:
Comparative study in intensity-modulated radiation therapy (IMRT) vs. 3D conformal planning for prostate adenoma
Authors:
Anca-Ștefania ORIAN(1), Claudia Gabriela CHILOM(1), Mihai DUMITRACHE(2)
Affiliation:
1)University of Bucharest, Faculty of Physics, 405 Atomistilor Street, P.O. Box MG-11, 077125 Magurele, Romania
2) Central Military Emergency University Hospital 'Dr. Carol Davila", Calea Plevnei nr. 134, Sector 1, Bucharest
E-mail
orian.anca@yahoo.com
Keywords:
Radiotherapy, intensity modulated radiation therapy, 3D conformal radiation therapy, dose-volume histograms
Abstract:
The main objective of the study is to highlight the differences between two treatment techniques in radiation therapy for prostate adenoma: Intensity-Modulated Radiation Therapy and 3D Conformal Radiation Therapy.
Radiation therapy evolved following the discovery of X-rays by W.C. Rӧntgen in 1895, the discovery of radioactivity in 1896, and the discovery of the radioactive elements radium and polonium by the Curie couple starting from 1898.
IMRT utilizes a radiation delivery system that allows for the adjustment of radiation beam intensity during treatment. This enables a more precise distribution of radiation dose to the target, allowing higher doses to be delivered to the tumor while sparing the surrounding healthy tissues. IMRT can be used in the treatment of complex tumors located near sensitive organs and enables a more precise conformation of the radiation beam to the shape of the target.
3D-CRT uses three-dimensional images of the tumor and surrounding healthy tissues to plan the treatment. The radiation beam is shaped according to the shape of the target and delivered in multiple beams to ensure uniform coverage of the target area. This technique is effective in treating tumors with regular shapes and can deliver precise radiation doses to the target while minimizing exposure to healthy tissues.
In comparison, 3D-CRT is more suitable for tumors with more regular shapes, such as convex ones, while IMRT can be used in the treatment of both convex and concave tumors, thanks to its ability to modulate the intensity of the radiation beam.
The primary objective of the study is to analyze dose-volume histograms, which are essential tools for obtaining a detailed evaluation of the treatment plan and optimizing the balance between tumor destruction and protection of healthy tissues. These histograms allow radiation therapists to evaluate and adjust the treatment to maximize effectiveness and minimize side effects.
References:
Duliu O. G., Dozimetrie și Radioprotecție, Editura nUniversitătii din Bucuresti, 2010
Erjona B., Ervis T., Elvisa K., Ferdinand R., Partizan M., Comparison of 3D CRT and IMRT tratment plans
Khan F. M., Gibbons, J. P. The Physics of Radiation Therapy
|
|
|
|