UNIVERSITY OF BUCHAREST
FACULTY OF PHYSICS

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2025-08-20 22:54

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Conference: Bucharest University Faculty of Physics 2025 Meeting


Section: Biophysics; Medical Physics


Title:
Advanced MRI Techniques for Pelvic Mass Evaluation


Authors:
Cosmin ADRIAN (1), Nicoleta CAZACU (2), Claudia G. CHILOM (3), Marilena GÎRBAN (2), Costin A. MINOIU (1)


Affiliation:
1) Clinical Emergency Hospital Bucharest, 014461 Bucharest, Romania

2) Smeeni Chronic Disease Hospital, Buzău, Romania

3) Department of Electricity, Solid Physics and Biophysics, Faculty of Physics, University of Bucharest, Măgurele, România, Postal address: 405, Atomiștilor St., CP MG - 11, București-Măgurele, RO - 077125, Romania



E-mail
s.nicoleta59@yahoo.ro 18.adriancosmin@gmail.com


Keywords:
MRI sequences, pelvic tumors, trade-off-parameters


Abstract:
Recent studies indicate a concerning rise in the incidence of pelvic tumors among younger adults [1,2]. Imaging techniques such as ultrasonography, computer tomography (CT), and magnetic resonance imaging (MRI) play a crucial role in the early detection and characterization of these tumors. Ultrasound is commonly the first-line imaging modality for pelvic mass evaluation, particularly in women. However in certain cases, its diagnostic performance may be limited by poor acoustic windows and restricted depth penetration. Similarly, while CT can help with pelvic examination, the limited soft-tissue contrast may make it difficult to differentiate complex structures. Magnetic resonance imaging (MRI), offering superior contrast resolution and tissue characterization, serves not only as a valuable alternative tool for ultrasonography and CT but also as a primary diagnostic modality in certain cases [3]. This study explores the role of various MRI sequences in characterizing pelvic lesions, focusing on the physical principles underlying tissue contrast, signal intensity variations, and diffusion properties. Image quality is closely related to the trade-off-parameters, spatial resolution, signal-to-noise ratio and total scan time. Balancing these factors can be challenging but understanding the physical principles and their applicable limits can aid in their optimal use. These aspects are important in the characterization of pelvic lesions where the appropriate selection of sequences and parameters plays a crucial role in differentiating benign from malignant lesions and establishing an accurate diagnosis. In conclusion, pelvic masses can be difficult to diagnose, but MRI is an important tool which can give to radiologists the key they need to overcome this difficulty because of its higher contrast resolution, anatomic detail, and tissue characterization. The understanding of how parameters and sequences influence the quality of acquired images, as well as an integrated medical perspective, contribute to the enhancement of diagnostic and clinical management of pelvic lesions.


References:

1. Erica di Martino, Lesley Smith, Stephen H. Bradley, Scott Hemphill, Judy Wright, Cristina Renzi, Rebecca Bergin, Jon Emery, and Richard D. Neal, Incidence trends for twelve cancers in younger adults—a rapid review, British Journal of Cancer 2022, 126:10, 1374-1386.

2. Fangjian Guo, Lyuba Levine, Abbey Berenson, Trends in the incidence of endometrial cancer among young women in the United States, 2001 to 2017, Journal of Clinical Oncology 2021, 39:15, 5578-5578.

3. Brian C. Allen, Keyanoosh Hosseinzadeh, Shadi A. Qasem, Adam Varner, and John R. Leyendecker, Practical Approach to MRI of Female Pelvic Masses, American Journal of Roentgenology 2014 202:6, 1366-1375