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UNIVERSITY OF BUCHAREST
FACULTY OF PHYSICS Guest
2025-08-20 22:57 |
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Conference: Bucharest University Faculty of Physics 2025 Meeting
Section: Biophysics; Medical Physics
Title:
Intensity-Modulated Radiation Therapy (IMRT) versus Volumetric Modulated Arc Therapy (VMAT) in Left-Sided Breast Cancer. A Comparison of Dosimetric Results
Authors:
Ioana ANTOCHI (1) , Mirabela DUMITRACHE (2) , Mihaela DUMITRACHE (2), Sanda VOINEA (1)
Affiliation:
1) Faculty of physics, university of Bucharest, 2) Coltea Clinic Hospital
E-mail
antochiioana12@gmail.com
Keywords:
MRT ,VMAT , dosimetric comparison , gamma analysis , DVH
Abstract:
Breast cancer is the most frequently diagnosed cancer among women worldwide, accounting for approximately 25% of all female cancer cases. Its global incidence continues to rise, especially in low- and middle-income countries. The control and prevention of breast cancer progression, particularly beyond stage II, depend on tumor complexity and the specialist’s decision regarding treatment selection and planning.In this study, two irradiation techniques were used: Intensity-Modulated Radiation Therapy (IMRT) and Volumetric Modulated Arc Therapy (VMAT). We compared the dosimetric results of 10 patients. For each patient, treatment plans were created using both techniques based on CT simulation images, delineation of target volumes and organs at risk (OAR) according to ICRU guidelines. The plans were quantitatively and qualitatively evaluated through isodose analysis and dose-volume histograms (DVH). Dose distributions were compared using the Gamma analysis method.The results showed that VMAT provided better coverage of the target volume, while IMRT achieved lower doses to organs at risk, including the heart, left lung, esophagus, and contralateral breast
References:
[1] E.B. Podgorsak. Radiation Oncology Physics: A Handbook for Teachers and Students.
International Atomic Energy Agency, Vienna, 2005.
[2] Faiz M. Khan and John P. Gibbons. Khan’s The Physics of Radiation Therapy.
Lippincott Williams & Wilkins, 6th edition, 2021.
[3] Faiz M. Khan. The physics of radiation therapy, 3rd edition, 2010.
[8] Ann Barrett, Stephen Morris, Jane Dobbs, and Tom Roques. Practical Radiotherapy
Planning. CRC Press, Boca Raton, FL, 2009.
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