UNIVERSITY OF BUCHAREST
FACULTY OF PHYSICS

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2024-11-22 2:05

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Conference: Bucharest University Faculty of Physics 2024 Meeting


Section: Biophysics; Medical Physics


Title:
Traceability and treatment of cervical cancer patients in the High Energy Radiotherapy Laboratory


Authors:
Irina - Maria DUMITRU (1,2), Mădălina CROITORIU (1,3), Amalia CONSTANTINESCU (1), Mircea SAVU (1), Ancuța-Elena BACIU (1)


Affiliation:
1. Institute of Oncology "Prof. Dr. Alexandru Trestioreanu", Fundeni 252, Sector 2, Bucharest

2. Faculty of Physics, University of Bucharest

3. Neolife Medical Center, Bucharest



E-mail
irinamaria_99@yahoo.com


Keywords:
Cervical cancer, external beam radiotherapy, brachytherapy


Abstract:
Cervical cancer is among the most common types of cancer affecting women worldwide. This scientific work highlights all the stages of preparation, scanning, planning, and verification of radiotherapeutic treatment for patients diagnosed with malignant cervical tumors and the delivery of treatment. Two types of treatment using ionizing radiation are presented and evaluated: External Beam Radiotherapy (EBRT) and three dimensional Intracavitary Brachytherapy High Dose Rate (3D-HDR) with a sealed source of Iridium 192. Planning, optimization, and quality assurance of treatment are precursor stages to quality assurance activities of radiological facilities and personnel training in the laboratory by medical physicists. The others of the medical activities and the delivery of treatment sessions fall within the responsibilities of medical assistants and radiotherapists. External Beam Radiotherapy (EBRT) is a standard treatment for cancer and the most common form of radiotherapy. It uses a machine to deliver beams of energy that destroy tumors. Brachytherapy is a treatment technique that uses sealed radiation sources (Ir192) to deliver a dose of radiation directly to the planned target volume (PTV). It allows precise delineation of the target and volumes of organs at risk. Conclusions: The treatment of this disease is radiochemotherapy, external RT, followed by brachytherapy, and in certain cases, surgical treatment. In early tumors, with small volume and low-grade staging, radiochemotherapy and intracavitary brachytherapy are indicated. 3D HDR brachytherapy allows the best coverage of the area by the reference dose with simultaneous protection of critical organs.


References:

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