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UNIVERSITY OF BUCHAREST
FACULTY OF PHYSICS Guest
2024-11-22 1:44 |
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Conference: Bucharest University Faculty of Physics 2024 Meeting
Section: Nuclear and Elementary Particles Physics
Title:
Production of Ga-68 on solid targets at the TR-19 cyclotron
Authors:
Andrei NECSOIU (1,2), Diana COCIOABA (1,2), Simona BARUTA (1), Dana NICULAE (1), Alexandru JIPA (2)
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Affiliation:
(1) Horia Hulubei National Institute for R&D in Physics and Nuclear Engineering (IFIN-HH)
(2) University of Bucharest, Doctoral School of Physics, Faculty of Physics
E-mail
andrei.necsoiu@nipne.ro
Keywords:
Ga-68, TR-19 cyclotron, solid target, PET imaging, TRIM
Abstract:
Gallium-68 is a radioisotope commonly used in nuclear Medicine, due to its decay characteristics and half-life of 68 min being suitable for Positron Emission Tomography (PET) imaging. It is often employed in conjunction with specific tracers that target specific tissues or biological processes, making it valuable for diagnostics in neuroendocrine tumours and prostate cancer. Moreover, its short half-life allows for high-resolution imaging while minimizing radiation exposure to patients.
This study presents the production method of Ga-68 radioisotope by proton irradiation of the Zn-68 target on the cyclotron, with an emphasis on the production on solid targets using the TR-19 cyclotron (CCR, IFIN-HH). For Zn-68(p,n)Ga-68 nuclear reaction, relevant experimental values of the production cross-section have been extracted from the nuclear database (Experimental Nuclear Reaction Data – EXFOR) and discussed in relation with TR-19 energy window. The optimal energy for this nuclear reaction correlated to the maximum value of cross section from the EXFOR database was estimated using TRIM simulation code (the Transport of Ions in Matter).
Acknowledgement:
The work was supported by the Romanian Ministry of Research, Innovation and Digitalization through project PN23210201 and IOSIN Ciclotron TR-19.
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