| |
 |
UNIVERSITY OF BUCHAREST
FACULTY OF PHYSICS Guest
2024-11-22 1:24 |
 |
|
|
|
Conference: Bucharest University Faculty of Physics 2024 Meeting
Section: Biophysics; Medical Physics
Title:
Biohybrids based on lipid nanoparticles, plant extracts and metallic nanoparticles: Biophysical aspects
Authors:
A.-E. CIUBOTARU (1), S. PETROVIC (2), M.-E. BARBINTA-PATRASCU (1)
Affiliation:
(1) University of Bucharest, Faculty of Physics, Department of Electricity, Solid-State Physics and Biophysics, 405 Atomistilor Street, PO Box MG-11, Bucharest-Magurele, 077125, Romania
(2) University of Nis, Faculty of Technology, Department of Chemical Technologies, Bulevar Oslobodjenja 124, 16000 Leskovac, Serbia
E-mail
marcela.barbinta@unibuc.ro
Keywords:
Green nanoparticles; liposomes; chlorophyll; urease activity
Abstract:
Green strategies are more and more used in nanotechnologies, considering the current global context. In this study, an eco-friendly approach was used to develop biohybrids containing liposomes, green AgNPs and vegetal extract. Fresh Citrus peels were used to generate silver nanoparticles (AgNPs). These nanoparticles were loaded into liposomes labeled with chlorophyll (Chl). Chl was used as an optical sensor to monitor in vitro, by UV-Vis absorption and fluorescence emission spectroscopy, the biohybrid development. The biohybrids were also characterized by FTIR ATR spectroscopy. Conductometric assay was used to check the potential inhibitory action against urease. Our findings show that the obtained biohybrids can be used in biomedical or in environmental applications to develop new urease inhibitors.
References:
1. Barbinta-Patrascu M.-E., Nichita C., Bita B., Antohe S., Biocomposite Materials Derived from Andropogon halepensis – Eco-design and Biophysical Evaluation, Materials, 17(5), 1225, 2024. https://doi.org/10.3390/ma17051225
2. Petrovic S.M., Barbinta-Patrascu M.-E., Organic and Biogenic Nanocarriers as Bio-Friendly Systems for Bioactive Compounds’ Delivery: State-of-the Art and Challenges. Materials, 16, 7550, 2023. https://doi.org/10.3390/ma16247550
3. Barbinta-Patrascu M.-E., Iftimie S., Cazacu N., Stan D.L., Costas A., Balan A.E., Chilom, C.G., Bio-Entities Based on Albumin Nanoparticles and Biomimetic Cell Membranes: Design, Characterization and Biophysical Evaluation. Coatings, 13(4), 671, 2023. https://doi.org/10.3390/coatings13040671
Acknowledgement:
The authors would like to thank the European Commission and CNCS/CCCDI-UEFISCDI for funding in the frame of the collaborative international consortium WaterGreenTreat financed under the 2022 Joint call of the European Partnership 101060874 — Water4All. This work was supported by a grant of the Ministry of Research, Innovation and Digitization, CNCS/CCCDI - UEFISCDI, project number COFUND-WATER4ALL-WATER Green Treat-1, No. 59/2024, within PNCDI IV.
|
|
|
|